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SBN Gut – Treat Irritable Gut Syndrome Naturally With Nucleotides & Support Gut Health
SBN Gut is based on a scientifically sound and balanced mixture of nucleotides with maximum bioavailability. These are supplemented with B vitamins, amino acids and fructooligosaccharides (FOS) to support healthy intestinal function.
They also support a healthy intestinal mucosa, the immune system and natural cell division. They ensure healthy intestinal flora and improve metabolism.
Why Gut Health is so Important

The gut as a key organ for the immune system and well-being
With a length of up to 8 metres and a surface area of approx. 400 m², the gut is the largest contact organ in our body. Every day, it decides which nutrients are absorbed and which substances are excreted. This makes it central to energy, well-being and a strong immune system.
Intestinal flora, mucous membrane and barrier function in balance
Over 1,000 species of bacteria live in our intestinal flora. If this microbiome is in balance, harmful germs are displaced and the mucous membrane remains intact. Stress, unhealthy eating habits or illness can disrupt this balance, resulting in complaints such as flatulence, cramps or irritable bowel symptoms.
Nucleotides – Small Building Blocks With A Big Impact
Why intestinal cells need millions of new nucleotides every day
The intestinal mucosa renews itself extremely quickly. Small intestine cells live for an average of only 36 hours – several hundred million cells are replaced every day. The body needs billions of nucleotides for this renewal, only some of which it can produce itself.
Diet is often insufficient – where SBN Gut comes in
Although nucleotides are found in food, only a fraction is directly available to the intestine. This is where SBN Gut comes in: easily accessible nucleotides support natural cell renewal and strengthen the intestinal barrier.

Treating irritable bowel syndrome – the role nucleotides can play

Typical symptoms of irritable bowel syndrome (IBS)
Around 25% of people in industrialised nations suffer from irritable bowel syndrome. Women are affected twice as often as men. Typical symptoms include flatulence, abdominal pain, diarrhoea, constipation and bloating.
How SBN Gut supports the intestinal mucosa in regeneration and balance
In irritable bowel syndrome, the mucosa and microbiome are often out of balance. SBN Darm provides nucleotides that promote cell repair and thus support the mucosa in its natural regeneration. In addition, FOS support the growth of beneficial intestinal bacteria and contribute to a better balance in the microbiome.
Scientific evidence on the effect of nucleotides in the intestine
Studies show that nucleotides can promote the regeneration of the intestinal mucosa, stabilise the microbiome and improve the barrier function. Initial results give reason to hope that a dietary supplement such as SBN Gut can provide useful support for people with irritable bowel symptoms – without promising a cure, but with scientific backing.
What Makes SBN Gut So Special?
The combination of nucleotides, B vitamins, amino acids & FOS
SBN Gut combines nucleotides with B vitamins, amino acids and prebiotic fibre (FOS). This combination supports digestion, the microbiome and metabolism in a holistic way.
Natural, well tolerated & scientifically proven
The ingredients are of natural origin, highly bioavailable and safe to use. Studies confirm the role of nucleotides in cell renewal and gut health.

Who Is SBN Gut Suitable For?

For digestive problems and sensitive bowel function
Ideal for people with sensitive digestive systems who want to support their intestinal health naturally.
Support during stressful periods
Stress is a common trigger for intestinal problems. SBN Gut provides building blocks that the body urgently needs during such times.
Supplement for irritable bowel syndrome to strengthen the microbiome and barrier
If you are looking for a natural supplement to treat irritable bowel syndrome holistically, SBN Gut can promote the natural regeneration of the intestinal mucosa and healthy intestinal flora.
Conclusion – Holistic treatment for irritable gut syndrome
SBN Gut as a ‘repair kit’ for the gut
With its unique composition, SBN Gut supports cell renewal, strengthens the intestinal barrier and promotes healthy gut flora.
A natural boost for greater intestinal comfort and well-being
Whether for irritable bowel symptoms, digestive problems or as preventive support, SBN Gut is a useful supplement for anyone who wants to strengthen their intestinal health and treat irritable bowel naturally.


Scientifically based
Dr. rer. nat. Peter Damian Koeppel, biochemist/immunologist and virologist, is the world's leading researcher in the field of nucleotides. He has been researching nucleotides and their nutritional significance for more than 30 years. Dr Koeppel and his team have demonstrated in more than 400 research reports and studies how beneficial and necessary it is to supplement the diet with nucleotides.
SBN Gut is perfect for you if:
- You want to actively support your gut health
- You want to promote the regeneration of the intestinal mucosa
- You value an intact microbiome and stable gut flora
- You want to harmonise your digestion and reduce symptoms such as flatulence or bloating.
- You are seeking a natural remedy for irritable bowel syndrome symptoms
- You prefer a scientifically proven product
- You want all this – and with just one simple daily dose
Ingredients
Nucleotides 28%; L-glutamine; fructo-oligosaccharides; hydroxypropyl methylcellulose (capsule shell); inositol; L-lysine; L-methionine; acidity regulator (sodium citrate); calcium D-pantothenate; vitamin B2 (riboflavin); (6S)-5-methyltetrahydrofolic acid; glucosamine salt; D-biotin
Take 3 capsules daily with some liquid during the first month.
After that, take 2 capsules daily.
Ingredient |
3 Capsules | % NRV* |
Pantothenic Acid | 9,0 mg | 150 |
Riboflavin | 2,8 mg | 200 |
Folic Acid | 400 μg | 200 |
Biotin | 125 μg | 250 |
Nucleotides | 417 mg | ** |
Glutamine | 381 mg | ** |
Lysine | 112 mg | ** |
Methionine | 81 mg | ** |
*) Nutrient Reference Values, NRV
**No NRV established
Storage: Cool, dry, protected from light
Net quantity: 60 capsules
Keep out of reach of small children. Do not exceed the recommended daily dose. Food supplements are not a substitute for a varied diet.
Nucleotides And The Gut: Questions & Answers
People with IBS often try to combat their symptoms with a restrictive diet. Unfortunately, this leads to a deficiency in essential nutrients – including food nucleotides – which is not conducive to the important regeneration process. The replenishment of dietary building blocks for the body's repair and natural cell regeneration process is of great importance for maintaining efficient bowel function and good intestinal health and balance.
The intestine needs the nutrients contained in SBN Intestine to maintain an optimal cell renewal rate and to repair the intestine. These nutrients provide the building blocks for new cells and support active cell renewal and proliferation whenever necessary.
Nucleotides are the basic building blocks of our DNA and therefore essential building blocks for new cells. In the intestine, cells of the intestinal mucosa are renewed extremely quickly – some small intestine cells only live for around 36 hours. To enable this constant renewal, the intestine needs a large number of nucleotides, but the intestinal cells themselves cannot produce nearly enough of them. They are therefore dependent on external sources. However, only a fraction of the required nucleotides can be absorbed through normal food. SBN Intestine provides extra easily available nucleotides to meet this need, thus contributing significantly to a robust intestinal structure, good digestion and optimal nutrient absorption.
SBN Darm is a natural dietary supplement in capsule form that contains a scientifically proven blend of nucleotides, B vitamins, amino acids and fructooligosaccharides (FOS). This special formula has been developed to support healthy bowel function. Specifically, SBN Darm promotes an intact intestinal mucosa and balanced intestinal flora, which promotes regular and efficient digestion. It also improves nutrient metabolism, allowing your body to better absorb and utilise nutrients from food. Overall, SBN Darm helps prevent gastrointestinal complaints and increases general abdominal well-being.
SBN Gut has been proven to strengthen the intestinal flora (microbiome) and ensure a healthy balance of bacteria in the gut. The capsules contain FOS, a prebiotic fibre that serves as food for beneficial gut bacteria, allowing ‘good’ bacteria such as bifidobacteria to multiply more effectively. At the same time, the nucleotides in SBN Gut provide important building blocks that some beneficial gut bacteria depend on. A strengthened community of good bacteria creates an environment in which harmful germs find it much more difficult to establish themselves. An intact intestinal flora effectively wards off unwanted intruders, reducing the frequency of problems such as flatulence or diarrhoea.
Yes. In fact, around 70% of the body's immune cells are located in the gut, where defence cells must be constantly renewed in order to neutralise pathogens from food. The body needs large amounts of nucleotides to form new defence cells and antibodies, but the immune cells cannot produce these building blocks themselves.
This is where SBN Gut comes in: the readily available nucleotides in the capsules provide the immune system in the gut with exactly the resources it needs to rapidly produce new defence cells. SBN Gut thus supports the immune defence of the gut and, as a result, also strengthens the body's overall resistance. Many users report that they feel less ill since their gut has been supported with SBN Gut.
The intestinal mucosa is constantly renewing itself, especially after stress or gastrointestinal infections. Prolonged stress or harmful germs can cause microscopic tears in the intestinal wall (often referred to as ‘leaky gut’) and promote inflammation. To repair such damage, the body must quickly produce new cells, which requires increased amounts of nucleotides as building material.
SBN Gut acts as a repair kit for the gut: the concentrated nucleotides in this product optimise cell renewal and repair and help restore a healthy, intact intestinal mucosa. A robust intestinal mucosa is important for optimal nutrient absorption and to prevent germs or toxins from entering the body.
SBN Darm can be a valuable aid in treating irritable bowel syndrome (IBS) and similar digestive complaints. Such problems are often accompanied by a damaged intestinal barrier, inflammation or disturbed intestinal flora – frequently triggered by stress or poor nutrition. SBN Gut provides the irritated gut with the building blocks it needs for repair and regeneration, allowing the intestinal wall to recover more quickly and the microbiome to regain its balance.
Unlike purely symptomatic treatments, SBN Gut tackles the root cause by promoting intestinal cell renewal and strengthening the gut's defences. Initial studies with the unique nucleotide formula of SBN Gut give reason to hope that this product can bring noticeable progress for those affected – many users report less flatulence, more regular digestion and an overall better quality of life.
SBN Gut is suitable for all adults (and even children) who want to actively support their gut health. It can be taken both preventively – i.e. to prevent digestive problems – and as an adjunct to existing problems. SBN Gut is ideal for virtually all population groups, including children and adults, people with stressful jobs, pregnant or breastfeeding women, and athletes who have increased nutritional needs.
People who are frequently under stress, suffer from a sensitive gastrointestinal tract or want to strengthen their immune system can particularly benefit from SBN Gut. As the product is natural and well tolerated, it is suitable for long-term use by anyone who wants to keep their digestion and intestinal flora in balance.
The recommended dosage for SBN Gut is simple: in the initial phase, it is recommended to take 3 capsules daily (spread throughout the day, ideally with meals). From the second month onwards, the dosage can be reduced to 2 capsules daily, depending on your needs, in order to maintain the achieved intestinal condition.
The first positive changes – such as a calmer digestive tract or greater well-being – often occur after just a few weeks of continuous use. For a lasting effect, it is advisable to take SBN Gut for at least four to eight weeks. As the product is well tolerated, it can also be used over a longer period or as a course of treatment, for example during stressful times or after a course of antibiotics, to rebuild the intestinal flora.
SBN Gut is considered very safe. The nucleotides it contains are derived from natural yeast and correspond to the substances that the body also extracts from food. Extensive studies on animals and humans have shown that daily supplementation with nucleotides is safe – excess amounts are simply stored by the body and there are no known undesirable side effects.
However, it is important to note certain precautions: SBN Gut should not be taken if you have gout, autoimmune diseases or immediately after an organ transplant. In such cases, be sure to consult your doctor. SBN Gut is generally very well tolerated by healthy individuals; there are no known interactions with medications, and the product can also be used during pregnancy or breastfeeding after consulting a doctor.
A balanced diet provides some nucleotides, and the body also recycles some of them from dead cells. Nevertheless, additional intake is often beneficial, as modern eating habits contain less and less nucleotide-rich foods – for example, offal and certain types of fish and meat are rarely on the menu today. In addition, the intestinal cells can only absorb and utilise a fraction of the nucleotides present in food. During periods of high demand – such as during stress, intense physical exertion or during and after illness – the body's own production and food are often insufficient.
Nucleotides then become ‘conditionally essential’ nutrients, meaning that the body can no longer produce them in sufficient quantities under these circumstances. Targeted supplementation with SBN Gut closes this gap: it ensures that the gut always has enough nucleotides available to function optimally, regenerate and absorb nutrients, even when the diet is not perfect.
What does science say about nucleotides?
Animal studies on young rats show that a diet supplemented with nucleotides (AMP, GMP, IMP, CMP, UMP) promotes faster and better regeneration of the small intestine mucosa after chronic diarrhoea. Histologically, after recovery, the mucosa was more similar to the healthy control – with intact microstructure, more goblet cells and normal mitochondrial structure. This suggests that nucleotides are important nutrients for intestinal repair.
In rats with chronic diarrhoea, crucial enzyme activities in the iliopsoas muscle (including ATPase and citrate synthase) normalised after a nucleotide-rich diet. This means that a nucleotide-rich diet supports the restoration of mitochondrial energy production in the intestine, which is essential for cell regeneration and healthy function. Study on Pubmed
Yes. Studies conducted on animals and infants show that supplemental oral intake of nucleotides increases the diversity of the intestinal flora, reduces pathogenic bacteria and improves the balance in favour of beneficial fermentative bacteria. This creates a more stable intestinal environment for better digestion and protection.
In early stages of growth – e.g. in infants – nucleotides function as so-called ‘conditionally essential’ nutrients. They support the normal development, maturation and repair of the gastrointestinal tract. The nucleotide composition in breast milk in particular shows how important they are in the young intestine.
A recent review from 2025 describes how nucleotides can promote the proliferation of intestinal mucosal cells and prevent pathogens from attaching to the intestinal wall. This maintains the barrier function and thus strengthens the overall integrity of the intestine. In addition, a diet containing nucleotides appears to increase the activity of beneficial intestinal bacteria (e.g. Lactobacillus), which further supports the intestine's defence potential.
Conclusion for interested parties:
Science clearly shows that under stress – such as stress, digestive problems or after infections – nucleotides can specifically support intestinal cells in regeneration and development, strengthen the barrier function and balance the microbiome.
These effects are well documented and give confidence in the benefits of supplementation – without having to make unrealistic healing promises.
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